Anti-IL-10RB/IL-10R2抗体(ab106282)
Key features and details
- Rabbit polyclonal to IL-10RB/IL-10R2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IL-10RB/IL-10R2抗体
参阅全部 IL-10RB/IL-10R2 一抗 -
描述
兔多克隆抗体to IL-10RB/IL-10R2 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human fetal heart, liver, kidney and muscle lysates
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 200ul distilled H2O. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106282于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use at an assay dependent concentration.
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WB |
1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
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说明 |
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IHC-P
Use at an assay dependent concentration. |
WB
1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa). |
靶标
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功能
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29. -
疾病相关
Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) [MIM:612567]. It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. -
序列相似性
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3588 Human
- Entrez Gene: 16155 Mouse
- Entrez Gene: 304091 Rat
- Omim: 123889 Human
- SwissProt: Q08334 Human
- SwissProt: Q61190 Mouse
- Unigene: 654593 Human
- Unigene: 4154 Mouse
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别名
- Cd210 antibody
- CDw210b antibody
- CRF2 4 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab106282 被引用在 1 文献中.
- Reemann P et al. Expression of class II cytokine genes in children's skin. Acta Derm Venereol 94:386-92 (2014). PubMed: 24284923