Anti-IGFBP6抗体(ab109765)
Key features and details
- Goat polyclonal to IGFBP6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IGFBP6抗体
参阅全部 IGFBP6 一抗 -
描述
山羊多克隆抗体to IGFBP6 -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Sheep, Cow, Pig -
免疫原
Synthetic peptide:
C-RPQDVNRRDQQRNP
, corresponding to internal sequence amino acids 128-141 of Human IGFBP6 -
阳性对照
- Human Skeletal Muscle tissue and Human Adrenal Gland lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab109765于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 25 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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说明 |
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WB
Use a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 25 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
靶标
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功能
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. -
序列相似性
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain. -
翻译后修饰
O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylated on one site only in the region AA 143-168 in cerebrospinal fluid. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 404186 Cow
- Entrez Gene: 3489 Human
- Omim: 146735 Human
- SwissProt: Q05718 Cow
- SwissProt: P24592 Human
- Unigene: 274313 Human
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别名
- IBP 6 antibody
- IBP-6 antibody
- IBP6 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (4)
ab109765 被引用在 4 文献中.
- Chen H et al. Alterations of mRNA and lncRNA profiles associated with the extracellular matrix and spermatogenesis in goats. Anim Biosci 35:544-555 (2022). PubMed: 34530511
- Nikulin S et al. Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells. Front Genet 12:662843 (2021). PubMed: 34149804
- Silva LM et al. Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome. Mol Cell Proteomics 18:818-836 (2019). PubMed: 30705123
- Zeng C et al. Decreased expression of insulin-like growth factor binding protein 6 is associated with gastric adenocarcinoma prognosis. Oncol Lett 13:4161-4168 (2017). PubMed: 28588703