Anti-IGF2抗体[RM0100-3J42] (ab86485)
Key features and details
- Rat monoclonal [RM0100-3J42] to IGF2
- Suitable for: Sandwich ELISA
- Reacts with: Rat
- Isotype: IgG2
概述
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产品名称
Anti-IGF2抗体[RM0100-3J42]
参阅全部 IGF2 一抗 -
描述
大鼠单克隆抗体[RM0100-3J42] to IGF2 -
宿主
Rat -
经测试应用
适用于: Sandwich ELISAmore details -
种属反应性
与反应: Rat -
免疫原
Recombinant full length Mouse protein
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯化说明
The IgG fraction of culture supernatant was purified by protein A/G affinity chromatography and 0.2µm filtered. -
克隆
单克隆 -
克隆编号
RM0100-3J42 -
同种型
IgG2 -
研究领域
相关产品
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Compatible Secondaries
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sELISA pair antibody
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab86485于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Sandwich ELISA |
Use a concentration of 1 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to IGF2 (ab18954).
For sandwich ELISA, use this antibody as Capture at 1µg/ml with ab18954 as Detection. |
说明 |
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Sandwich ELISA
Use a concentration of 1 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to IGF2 (ab18954). For sandwich ELISA, use this antibody as Capture at 1µg/ml with ab18954 as Detection. |
靶标
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功能
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3. -
疾病相关
Epigenetic changes of DNA hypomethylation in IGF2 are a cause of Silver-Russell syndrome (SIRS) [MIM:180860]. SIRS is a clinically heterogeneous condition characterized by severe intrauterine growth retardation, poor postnatal growth, craniofacial features such as a triangular shaped face and a broad forehead, body asymmetry, and a variety of minor malformations. -
序列相似性
Belongs to the insulin family. -
翻译后修饰
O-glycosylated with a core 1 or possibly core 8 glycan. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 24483 Rat
- SwissProt: P01346 Rat
- Unigene: 118681 Rat
- Unigene: 224460 Rat
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别名
- C11orf43 antibody
- IGF 2 antibody
- IGF II antibody
see all
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab86485 尚未被引用在任何文献中。