生物素抗人Serum Albumin抗体[AL-01] (ab81426)
Key features and details
- Biotin Mouse monoclonal [AL-01] to Human Serum Albumin
- Suitable for: WB
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
概述
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产品名称
生物素抗人Serum Albumin抗体[AL-01]
参阅全部 Human Serum Albumin 一抗 -
描述
生物素小鼠单克隆抗体[AL-01] to人Serum Albumin -
宿主
Mouse -
偶联物
Biotin -
特异性
Reacts only with Human Serum Albumin. No cross-reactivity was observed with other serum proteins. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
不与反应: Mammals -
免疫原
Full length native protein (purified) corresponding to Human Human Serum Albumin. Fraction of proteins containing Albumin after ammonnium sulphate precipitation and DEAE-chromatography of Human serum.
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阳性对照
- WB: Human plasma.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Size exclusion -
克隆
单克隆 -
克隆编号
AL-01 -
同种型
IgG1 -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab81426于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 2 - 5 µg/ml. Predicted molecular weight: 69 kDa.
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说明 |
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WB
Use a concentration of 2 - 5 µg/ml. Predicted molecular weight: 69 kDa. |
靶标
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功能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
组织特异性
Plasma. -
疾病相关
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
序列相似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
翻译后修饰
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
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别名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
图片
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All lanes : Biotin Anti-Human Serum Albumin antibody [AL-01] (ab81426) at 5 µg/ml
Lane 1 : Human plasma (non-reducing conditions)
Lane 2 : Human plasma (reducing conditions)
Lane 3 : HeLa (Human epithelial cell line from cervix adenocarcinoma) cell lysate (reducing conditions)
Secondary
All lanes : IRDye800-conjugated Streptavidin
Predicted band size: 69 kDaThe experiment was conducted under reducing and non-reducing conditions.Negative control: HeLa cell lysate.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab81426 被引用在 1 文献中.
- Edwards W et al. Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-life. J Biol Chem 289:22704-14 (2014). ELISA . PubMed: 24939846