人Retinoic Acid Receptor gamma 2多肽(ab39774)
Key features and details
- Purity: > 90% SDS-PAGE
- Suitable for: Neutralising, Blocking
描述
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产品名称
人Retinoic Acid Receptor gamma 2多肽 -
纯度
> 90 % SDS-PAGE. -
无动物成分
No -
性质
Synthetic -
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种属
Human -
序列
RRLYGAAGPGAGLLRR -
氨基酸
13 to 28
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技术指标
Our Abpromise guarantee covers the use of ab39774 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Neutralising
Blocking
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
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复溶Reconstitute with 0.1 ml of distilled water.
常规信息
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别名
- NR1B3
- Nuclear receptor subfamily 1 group B member 3
- RAR gamma
see all -
功能
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. -
序列相似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
结构域
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab39774 尚未被引用在任何文献中。