人KMT4 / Dot1L多肽(ab71337)
Key features and details
- Purity: > 70% HPLC
- Suitable for: Blocking
描述
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产品名称
人KMT4 / Dot1L多肽
参阅全部 KMT4 / Dot1L 蛋白酶 -
纯度
> 70 % HPLC.
70 - 90% by HPLC -
Accession
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无动物成分
No -
性质
Synthetic -
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种属
Human
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技术指标
Our Abpromise guarantee covers the use of ab71337 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Blocking
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形式
Liquid -
补充说明
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
常规信息
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别名
- Disrupter of telomere silencing protein 1
- DOT 1
- DOT1
see all -
功能
Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. -
序列相似性
Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
Contains 1 DOT1 domain. -
细胞定位
Nucleus. - Information by UniProt
图片
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To learn more about our protein and peptide range click here.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab71337 被引用在 1 文献中.
- Ooga M et al. Involvement of DOT1L in the remodeling of heterochromatin configuration during early preimplantation development in mice. Biol Reprod 89:145 (2013). Blocking . PubMed: 24132959