Anti-HO-2抗体(ab90515)
Key features and details
- Rabbit polyclonal to HO-2
- Suitable for: WB, ICC/IF, IHC-P, IP, ELISA
- Reacts with: Mouse, Rat, Hamster, Dog, Human, Pig, Monkey
- Isotype: IgG
概述
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产品名称
Anti-HO-2抗体
参阅全部 HO-2 一抗 -
描述
兔多克隆抗体to HO-2 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IF, IHC-P, IP, ELISAmore details -
种属反应性
与反应: Mouse, Rat, Hamster, Dog, Human, Pig, Monkey -
免疫原
Synthetic peptide corresponding to Human HO-2 (N terminal).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab90515于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (3) |
1/1000. Predicted molecular weight: 36 kDa.
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ICC/IF |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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说明 |
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WB
1/1000. Predicted molecular weight: 36 kDa. |
ICC/IF
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
靶标
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功能
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter. -
序列相似性
Belongs to the heme oxygenase family.
Contains 2 HRM (heme regulatory motif) repeats. -
细胞定位
Microsome. Endoplasmic reticulum. - Information by UniProt
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数据库链接
- Entrez Gene: 479864 Dog
- Entrez Gene: 3163 Human
- Entrez Gene: 15369 Mouse
- Entrez Gene: 79239 Rat
- Omim: 141251 Human
- SwissProt: P30519 Human
- SwissProt: O70252 Mouse
- SwissProt: P23711 Rat
see all -
别名
- Heme oxygenase (decycling) 2 antibody
- Heme oxygenase (decyclizing) 2 antibody
- Heme oxygenase 2 antibody
see all
图片
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ab90515 staining HO-2 in MCF7 cells by Immunofluorescence (green). Nuclei are stained in blue pseudocolor using DRAQ5.
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All lanes : Anti-HO-2 antibody (ab90515) at 1/1000 dilution
Lane 1 : HO-2 Recombinant Human Protein
Lane 2 : Human Liver Microsome Extract
Lane 3 : Mouse Liver Microsome Extract
Lane 4 : Rat Liver Microsome Extract
Lane 5 : Dog Liver Microsome Extract
Predicted band size: 36 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab90515 被引用在 5 文献中.
- Hanna DA et al. Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells. J Biol Chem 298:101549 (2022). PubMed: 34973332
- Patra U et al. Progressive Rotavirus Infection Downregulates Redox-Sensitive Transcription Factor Nrf2 and Nrf2-Driven Transcription Units. Oxid Med Cell Longev 2020:7289120 (2020). PubMed: 32322337
- Liu L et al. Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site. J Biol Chem 295:17227-17240 (2020). PubMed: 33051205
- Yang F et al. Suppression of TRPV4 channels ameliorates anti-dipsogenic effects under hypoxia in the subfornical organ of rats. Sci Rep 6:30168 (2016). WB . PubMed: 27436489
- Lee S et al. Chronic Stress Decreases Cerebrovascular Responses During Rat Hindlimb Electrical Stimulation. Front Neurosci 9:462 (2015). WB ; Rat . PubMed: 26778944