FITC荧光Anti-Heme Oxygenase 1抗体[HO-1-2] (ab69545)
Key features and details
- FITC Mouse monoclonal [HO-1-2] to Heme Oxygenase 1
- Suitable for: Flow Cyt (Intra)
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
概述
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产品名称
FITC荧光Anti-Heme Oxygenase 1抗体[HO-1-2]
参阅全部 Heme Oxygenase 1 一抗 -
描述
FITC荧光小鼠单克隆抗体[HO-1-2] to Heme Oxygenase 1 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
经测试应用
适用于: Flow Cyt (Intra)more details -
种属反应性
与反应: Human -
免疫原
Full length native protein (purified) (Rat)
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阳性对照
- Jurkat cells
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常规说明
This product was changed from ascites to tissue culture supernatant on 14th September 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purified from TCS -
克隆
单克隆 -
克隆编号
HO-1-2 -
同种型
IgG2b -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab69545于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt (Intra) |
Use a concentration of 100 µg/ml.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt (Intra)
Use a concentration of 100 µg/ml. ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. -
序列相似性
Belongs to the heme oxygenase family. -
细胞定位
Microsome. Endoplasmic reticulum. - Information by UniProt
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数据库链接
- Entrez Gene: 3162 Human
- Omim: 141250 Human
- SwissProt: P09601 Human
- Unigene: 517581 Human
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别名
- 32 kD antibody
- bK286B10 antibody
- D8Wsu38e antibody
see all
数据表及文件
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Datasheet download
文献 (6)
ab69545 被引用在 6 文献中.
- Lehrke MJ et al. The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice. Elife 10:N/A (2021). PubMed: 34762046
- Lei L et al. Dihydroquercetin Activates AMPK/Nrf2/HO-1 Signaling in Macrophages and Attenuates Inflammation in LPS-Induced Endotoxemic Mice. Front Pharmacol 11:662 (2020). PubMed: 32508636
- Ruan ZF et al. MiR-370 accelerated cerebral ischemia reperfusion injury via targeting SIRT6 and regulating Nrf2/ARE signal pathway. Kaohsiung J Med Sci 36:741-749 (2020). PubMed: 32311231
- Chiang N et al. Inhaled carbon monoxide accelerates resolution of inflammation via unique proresolving mediator-heme oxygenase-1 circuits. J Immunol 190:6378-88 (2013). PubMed: 23650615
- Walther M et al. HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children. PLoS Pathog 8:e1002579 (2012). Flow Cyt ; Human . PubMed: 22438807
- Mougiakakos D et al. The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells. Blood 117:4826-35 (2011). Flow Cyt ; Human . PubMed: 21389316