Anti-HPV16 E2抗体[TVG 261] (ab17185)
Key features and details
- Mouse monoclonal [TVG 261] to HPV16 E2
- Suitable for: ELISA, WB
- Reacts with: Human papillomavirus type 16
- Isotype: IgG1
概述
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产品名称
Anti-HPV16 E2抗体[TVG 261]
参阅全部 HPV16 E2 一抗 -
描述
小鼠单克隆抗体[TVG 261] to HPV16 E2 -
宿主
Mouse -
经测试应用
适用于: ELISA, WBmore details -
种属反应性
与反应: Human papillomavirus type 16 -
免疫原
Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE).
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表位
aa2-17 - ETLCQRLNVCQDKILT. -
常规说明
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 261 is useful for detection of protein in cervical lesions.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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纯度
Protein A/G purified -
Primary antibody说明
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 261 is useful for detection of protein in cervical lesions. -
克隆
单克隆 -
克隆编号
TVG 261 -
骨髓瘤
NS0/1 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab17185于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent dilution.
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WB | (2) |
Use at an assay dependent dilution. Predicted molecular weight: 42 kDa.
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说明 |
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ELISA
Use at an assay dependent dilution. |
WB
Use at an assay dependent dilution. Predicted molecular weight: 42 kDa. |
靶标
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别名
- HPV16 regulatory protein E2 antibody
- Human papilloma virus 16 E2 antibody
- Human papilloma virus 16 regulatory protein E2 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (11)
ab17185 被引用在 11 文献中.
- Prabhakar AT et al. CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle. mBio 12:e0116321 (2021). PubMed: 34544280
- Evans MR et al. Human Papillomavirus 16 E2 Regulates Keratinocyte Gene Expression Relevant to Cancer and the Viral Life Cycle. J Virol 93:N/A (2019). PubMed: 30518656
- Ludwig S et al. Molecular and Functional Profiles of Exosomes From HPV(+) and HPV(-) Head and Neck Cancer Cell Lines. Front Oncol 8:445 (2018). PubMed: 30370252
- Yuan R et al. Cardioprotective Effects of HuoxueAnshen Recipe against Myocardial Injuries Induced by Sleep Deprivation in Rats. Evid Based Complement Alternat Med 2017:7359760 (2017). PubMed: 28479928
- Evans MR et al. An oral keratinocyte life cycle model identifies novel host genome regulation by human papillomavirus 16 relevant to HPV positive head and neck cancer. Oncotarget 8:81892-81909 (2017). WB . PubMed: 29137231