Anti-FNIP1抗体(ab61395)
Key features and details
- Rabbit polyclonal to FNIP1
- Suitable for: IP, WB
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-FNIP1抗体
参阅全部 FNIP1 一抗 -
描述
兔多克隆抗体to FNIP1 -
宿主
Rabbit -
经测试应用
适用于: IP, WBmore details
不适用于: IHC-P -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide corresponding to FNIP1. A peptide at the N-terminus of FNIP1, MAPTLFQKLFSKRTGLGAC-amide
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab61395于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IP |
Use at an assay dependent concentration.
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WB | (1) |
Use at an assay dependent concentration.
|
说明 |
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IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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相关性
May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. -
细胞定位
Cytoplasm. Note: Co-localizes with FLCN in the cytoplasm. -
数据库链接
- Entrez Gene: 96459 Human
- Entrez Gene: 216742 Mouse
- Omim: 610594 Human
- SwissProt: Q8TF40 Human
- SwissProt: Q68FD7 Mouse
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别名
- KIAA1961 antibody
- FLCN-interacting protein antibody
- FNIP1 antibody
- Folliculin interacting protein 1 antibody
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab61395 被引用在 3 文献中.
- El-Houjeiri L et al. Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis. J Clin Invest 131:N/A (2021). PubMed: 34779410
- Siggs OM et al. Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity. Proc Natl Acad Sci U S A 113:E3706-15 (2016). PubMed: 27303042
- Liu J et al. Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med 8:1212-1228 (2016). PubMed: 27506764