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- Proteins and Peptides
- Secondary antibodies
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Product name
Anti-ERC1 antibody
参阅全部 ERC1 抗体 (5) ...
Description
Goat polyclonal to ERC1
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat
Immunogen
Synthetic peptide: YGSARSVGKVEPS, corresponding to N terminal amino acids 2-14 of Human ELKS.
YGSARSVGKVEPS
Positive control
Human Pancreas and Testis lysates
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Neuroscience >> Neurotransmission >> Secretory Vesicles >> Rabs
Neuroscience >> Neurotransmitter >> Transporters >> Other
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Western blot - ERC1 antibody (ab21192)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab21192 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 37 , 85 kDa.Can be blocked with ERC1 peptide (ab45484).
Target
Relevance
Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. The protein is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Five transcript variants encoding different isoforms have been found for this gene.
Cellular localization
Cytoplasmic. Membrane; peripheral membrane protein. Golgi apparatus; Golgi apparatus membrane; peripheral membrane protein.
Alternative names
- Cast 2 antibody
- CAST2 antibody
- CAZ-associated structural protein 2 antibody
see all
Database links
- Entrez Gene: 23085 Human
- Entrez Gene: 111173 Mouse
- Entrez Gene: 266806 Rat
- Omim: 607127 Human
- SwissProt: Q8IUD2 Human
- SwissProt: Q9BSG3 Human
- SwissProt: Q99MI1 Mouse
- SwissProt: Q99LQ6 Mouse
see all
Anti-ERC1 antibody images:
Western blot - ERC1 antibody (ab21192)
Anti-ERC1 antibody (ab21192) at 0.1 µg/ml + Tissue lysates prepared from human pancreas at 35 µg
References for Anti-ERC1 antibody (ab21192)
ab21192 has not yet been referenced specifically in any publications.
Publishing research using ab21192? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"