Anti-DOCK9/Trg抗体(ab70272)
Key features and details
- Rabbit polyclonal to DOCK9/Trg
- Suitable for: WB, IP
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-DOCK9/Trg抗体
参阅全部 DOCK9/Trg 一抗 -
描述
兔多克隆抗体to DOCK9/Trg -
宿主
Rabbit -
经测试应用
适用于: WB, IPmore details -
种属反应性
与反应: Human
预测可用于: Opossum, Orangutan -
免疫原
Synthetic peptide, corresponding to amino acids 1-50 of Human DOCK9 (NP_056111.1)
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阳性对照
- HeLa whole cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab70272于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/5000 - 1/15000. Detects a band of approximately 236 kDa (predicted molecular weight: 236 kDa).
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IP |
Use at 2-5 µg/mg of lysate.
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说明 |
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WB
1/5000 - 1/15000. Detects a band of approximately 236 kDa (predicted molecular weight: 236 kDa). |
IP
Use at 2-5 µg/mg of lysate. |
靶标
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功能
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation. -
组织特异性
Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle. -
序列相似性
Belongs to the DOCK family.
Contains 1 DHR-1 domain.
Contains 1 DHR-2 domain.
Contains 1 PH domain. -
结构域
The DHR-2 domain is necessary and sufficient for the GEF activity. -
细胞定位
Endomembrane system. Associated with membranes. - Information by UniProt
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数据库链接
- Entrez Gene: 23348 Human
- Omim: 607325 Human
- SwissProt: Q9BZ29 Human
- Unigene: 596105 Human
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别名
- Cdc42 guanine nucleotide exchange factor zizimin 1 antibody
- Cdc42 guanine nucleotide exchange factor zizimin-1 antibody
- Dedicator of cytokinesis protein 9 antibody
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图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab70272 被引用在 1 文献中.
- Wieczfinska J et al. The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res 16:147 (2015). WB . PubMed: 26646719