Anti-Cytochrome b245 Light Chain/p22-phox抗体[44.1] (ab80896)
Key features and details
- Mouse monoclonal [44.1] to Cytochrome b245 Light Chain/p22-phox
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG2
概述
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产品名称
Anti-Cytochrome b245 Light Chain/p22-phox抗体[44.1]
参阅全部 Cytochrome b245 Light Chain/p22-phox 一抗 -
描述
小鼠单克隆抗体[44.1] to Cytochrome b245 Light Chain/p22-phox -
宿主
Mouse -
特异性
This antibody is specific for Human Cytochrome b245 Light Chain/p22-phox 29-TAGRF-33 & 183-PQVNPI-188. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Full length protein corresponding to Human Cytochrome b245 Light Chain/p22-phox. Partially Purified human neutrophil flavocytochrome b (heparin Ultrogel/lectin affinity purification – in Triton X-100)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
44.1 -
骨髓瘤
Sp2/0 -
同种型
IgG2 -
研究领域
相关产品
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Compatible Secondaries
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab80896于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.
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说明 |
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WB
Use at an assay dependent dilution. Predicted molecular weight: 21 kDa. |
靶标
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相关性
Cytochrome b245 Light Chain/p22phox is a critical component of the membrane-bound oxidase complex that generates superoxide. It complexes with NOX3 to form a functional NADPH oxidase. -
细胞定位
Cell Membrane -
数据库链接
- Entrez Gene: 1535 Human
- Omim: 608508 Human
- SwissProt: P13498 Human
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别名
- CYBA antibody
- Cytochrome b 245 alpha polypeptide antibody
- Cytochrome b 245 light chain antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab80896 被引用在 8 文献中.
- Gong J et al. Alamandine alleviates hypertension and renal damage via oxidative-stress attenuation in Dahl rats. Cell Death Discov 8:22 (2022). PubMed: 35022384
- Dakik H et al. Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status. Antioxidants (Basel) 10:N/A (2021). PubMed: 33807114
- Hu Y et al. Downregulation of microRNA-106a-5p alleviates ox-LDL-mediated endothelial cell injury by targeting STAT3. Mol Med Rep 22:783-791 (2020). PubMed: 32626987
- Wang L et al. Methylophiopogonanone B of Radix Ophiopogonis protects cells from H2O2-induced apoptosis through the NADPH oxidase pathway in HUVECs. Mol Med Rep 20:3691-3700 (2019). PubMed: 31485606
- Ju HQ et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun 8:14437 (2017). WB . PubMed: 28232723
- Taylor RM & Jesaitis AJ Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics. Methods Mol Biol 412:429-37 (2007). PubMed: 18453126
- Burritt JB et al. Antibody imprint of a membrane protein surface. Phagocyte flavocytochrome b. J Biol Chem 273:24847-52 (1998). PubMed: 9733789
- Burritt JB et al. Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. J Biol Chem 270:16974-80 (1995). PubMed: 7622517