Cytochalasin B,actin polymerization抑制剂(ab143482)
Key features and details
- Cell permeable actin polymerization inhibitor. Reversible KV1.5 blocker.
- CAS Number: 14930-96-2
- Purity: > 97%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Drechslera dematoidea
概述
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产品名称
Cytochalasin B,actin polymerization抑制剂 -
描述
Cell permeable actin polymerization抑制剂. Reversible KV1.5 blocker. -
纯度
> 97% -
CAS编号
14930-96-2 -
化学结构
性能
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化学名称
(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione -
分子量
479.61 -
分子式
C29H37NO5 -
PubChem识别号
5311281 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 10 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]1CCC[C@@H](/C=C/C(=O)O[C@]23[C@@H](/C=C/C1)[C@@H](C(=C)[C@H]([C@H]2[C@@H](NC3=O)Cc4ccccc4)C)O)O -
来源
Drechslera dematoidea
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab143482 被引用在 2 文献中.
- Wang F et al. MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking. EMBO Rep 22:e52006 (2021). PubMed: 34096155
- Takahashi K et al. In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization. Sci Rep 8:15585 (2018). PubMed: 30348987