Anti-Cathepsin F抗体(ab36161)
Key features and details
- Goat polyclonal to Cathepsin F
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Cathepsin F抗体
参阅全部 Cathepsin F 一抗 -
描述
山羊多克隆抗体to Cathepsin F -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Dog -
免疫原
Synthetic peptide:
CGVNTMASSAVVD
, corresponding to C terminal amino acids 472-484 of Human Cathepsin F -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab36161于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
说明 |
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WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 53 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. -
组织特异性
High expression levels in heart, skeletal muscle, brain, testis and ovary; moderate levels in prostate, placenta, liver and colon; and no detectable expression in peripheral leukocytes and thymus. -
序列相似性
Belongs to the peptidase C1 family. -
细胞定位
Lysosome. - Information by UniProt
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数据库链接
- Entrez Gene: 8722 Human
- Entrez Gene: 56464 Mouse
- Omim: 603539 Human
- SwissProt: Q9UBX1 Human
- SwissProt: Q9R013 Mouse
- Unigene: 11590 Human
- Unigene: 29561 Mouse
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别名
- AI481912 antibody
- CATF_HUMAN antibody
- Cathepsin F antibody
see all
图片
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Anti-Cathepsin F antibody (ab36161) at 0.3 µg/ml + Human Ovary lysate (35µg protein in RIPA buffer).
Predicted band size: 53 kDa
Primary incubation was 1 hour. Detected by chemiluminescence.Experiments gave bands at approx 30kDa and 35kDa in Human Prostate and Ovary lysates after 0.3µg/ml antibody staining. These bands correspond to earlier findings in literature (Wang et al, J Biol Chem. 1998 Nov 27;273(48):32000-8; PMID: 9822672). This protein has a calculated MW of 53.4kDa according to NP_003784.2.
数据表及文件
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Datasheet download
文献 (1)
ab36161 被引用在 1 文献中.
- Jeric B et al. N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions. Biochim Biophys Acta 1833:2254-66 (2013). Human . PubMed: 23684953