Anti-Catalase抗体(ab50434)
Key features and details
- Goat polyclonal to Catalase
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Catalase抗体
参阅全部 Catalase 一抗 -
描述
山羊多克隆抗体to Catalase -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Guinea pig, Cow, Dog, Common marmoset, Orangutan -
免疫原
Synthetic peptide:
C-DKYNAEKPKNAIHT
, corresponding to internal sequence amino acids 498-511 of Human Catalase -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab50434于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa).
1 hour primary incubation is recommended for this product. |
IHC-P |
Use a concentration of 2 - 4 µg/ml.
|
说明 |
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WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa). 1 hour primary incubation is recommended for this product. |
IHC-P
Use a concentration of 2 - 4 µg/ml. |
靶标
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功能
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. -
疾病相关
Defects in CAT are the cause of acatalasia (ACATLAS) [MIM:115500]; also known as acatalasemia. This disease is characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions. -
序列相似性
Belongs to the catalase family. -
翻译后修饰
The N-terminus is blocked. -
细胞定位
Peroxisome. - Information by UniProt
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数据库链接
- Entrez Gene: 531682 Cow
- Entrez Gene: 403474 Dog
- Entrez Gene: 847 Human
- Entrez Gene: 12359 Mouse
- Omim: 115500 Human
- SwissProt: P00432 Cow
- SwissProt: O97492 Dog
- SwissProt: P04040 Human
see all -
别名
- Cas1 antibody
- CAT antibody
- CATA_HUMAN antibody
see all
图片
数据表及文件
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Datasheet download
文献 (4)
ab50434 被引用在 4 文献中.
- Biyik I et al. The effects of recombinant klotho in cisplatin-induced ovarian failure in mice. J Obstet Gynaecol Res 47:1817-1824 (2021). PubMed: 33611838
- Block A et al. The GABAAa5-selective Modulator, RO4938581, Rescues Protein Anomalies in the Ts65Dn Mouse Model of Down Syndrome. Neuroscience 372:192-212 (2018). PubMed: 29292072
- Xie W et al. Exercise training-enhanced, endothelium-dependent dilation mediated by altered regulation of BK(Ca) channels in collateral-dependent porcine coronary arterioles. Microcirculation 20:170-82 (2013). PubMed: 23002811
- Habib LK et al. Inhibitors of Catalase-Amyloid Interactions Protect Cells from {beta}-Amyloid-Induced Oxidative Stress and Toxicity. J Biol Chem 285:38933-43 (2010). IP ; Human . PubMed: 20923778