Anti-H-FABP抗体[66E2] (ab16915)
Key features and details
- Mouse monoclonal [66E2] to H-FABP
- Suitable for: IHC-Fr
- Reacts with: Human
- Isotype: IgG1
概述
-
产品名称
Anti-H-FABP抗体[66E2]
参阅全部 H-FABP 一抗 -
描述
小鼠单克隆抗体[66E2] to H-FABP -
宿主
Mouse -
特异性
ab16915 binds to H-FABP and shows no cross reactivity to human intestinal or liver FABP
-
经测试应用
适用于: IHC-Frmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Pig -
免疫原
Full length native protein (purified) corresponding to Human H-FABP.
-
阳性对照
- Heart cells, or recombinant H-FABP
-
常规说明
This antibody can be used to detect ischemia areas of human heart. It is also useful as marker for brain damage.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
-
纯度
Protein G purified -
纯化说明
Provided as a 0.2µm filtered antibody solution. -
Primary antibody说明
This antibody can be used to detect ischemia areas of human heart. It is also useful as marker for brain damage. -
克隆
单克隆 -
克隆编号
66E2 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab16915于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-Fr |
Use at an assay dependent concentration.
|
说明 |
---|
IHC-Fr
Use at an assay dependent concentration. |
靶标
-
功能
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. -
序列相似性
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. -
结构域
Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. -
细胞定位
Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 2170 Human
- Entrez Gene: 14077 Mouse
- Entrez Gene: 399532 Pig
- Entrez Gene: 79131 Rat
- Omim: 134651 Human
- SwissProt: P05413 Human
- SwissProt: P11404 Mouse
- SwissProt: O02772 Pig
see all -
别名
- 422 protein antibody
- Cardiac FABP antibody
- Cardiac Fatty Acid Binding Protein antibody
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (8)
ab16915 被引用在 8 文献中.
- Hung KC et al. Effect of N‑terminal region of human parvovirus B19‑VP1 unique region on cardiac injury in naïve mice. Mol Med Rep 24:N/A (2021). PubMed: 34476499
- Hersrud SL et al. Plasma biomarkers for neuronal ceroid lipofuscinosis. FEBS J 283:459-71 (2016). PubMed: 26565144
- Abbasi A et al. Myocardial macronutrient transporter adaptations in the adult pregestational female intrauterine and postnatal growth-restricted offspring. Am J Physiol Endocrinol Metab 302:E1352-62 (2012). Rat . PubMed: 22338075
- Mousiolis AV et al. Effects of leptin on the expression of fatty acid-binding proteins in human placental cell cultures. Mol Med Rep 5:497-502 (2012). PubMed: 22109570
- Lewis C et al. Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Proteins. J Biomed Biotechnol 2010:648501 (2010). WB ; Mouse . PubMed: 20508850
- Elmasri H et al. Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. FASEB J 23:3865-73 (2009). PubMed: 19625659
- Nevo J et al. Mammary-derived growth inhibitor alters traffic of EGFR and induces a novel form of cetuximab resistance. Clin Cancer Res 15:6570-81 (2009). WB ; Human . PubMed: 19825952
- Heather LC et al. Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart. Cardiovasc Res 72:430-7 (2006). PubMed: 17034771