Anti-Homeobox蛋白cut-like 1抗体(ab73885)
Key features and details
- Rabbit polyclonal to Homeobox protein cut-like 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Homeobox蛋白cut-like 1抗体
参阅全部 Homeobox protein cut-like 1 一抗 -
描述
兔多克隆抗体to Homeobox蛋白cut-like 1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Synthetic peptide corresponding to Human Homeobox protein cut-like 1 (N terminal).
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阳性对照
- WB: Extracts from K562 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab73885于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 164 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 164 kDa. |
靶标
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相关性
Function: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). Similarity: Belongs to the CUT homeobox family. -
细胞定位
Nucleus -
数据库链接
- Entrez Gene: 1523 Human
- Omim: 116896 Human
- SwissProt: P39880 Human
- SwissProt: P70403 Mouse
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别名
- CCAAT displacement protein antibody
- CDP antibody
- CDP/Cut antibody
see all
图片
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All lanes : Anti-Homeobox protein cut-like 1 antibody (ab73885) at 1/500 dilution
Lane 1 : extracts from K562 cells
Lane 2 : extracts from K562 cells with immunizing peptide at 10 µg
Lysates/proteins at 20 µg per lane.
Predicted band size: 164 kDa
Observed band size: 164 kDa
Additional bands at: 75 kDa, 80 kDa. We are unsure as to the identity of these extra bands.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab73885 被引用在 1 文献中.
- Wong CC et al. Inactivating CUX1 mutations promote tumorigenesis. Nat Genet 46:33-8 (2014). WB . PubMed: 24316979