Anti-GULP抗体(ab97669)
Key features and details
- Rabbit polyclonal to GULP
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
-
产品名称
Anti-GULP抗体
参阅全部 GULP 一抗 -
描述
兔多克隆抗体to GULP -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat -
免疫原
Synthetic peptide corresponding to Human GULP aa 241-304.
Database link: NP_057399 -
阳性对照
- 293T, HeLa, HepG2, MOLT4 or NIH3T3 cell lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97669于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 35 kDa.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 35 kDa. |
靶标
-
功能
May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. -
组织特异性
Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. -
序列相似性
Belongs to the ced-6 family.
Contains 1 PID domain. -
细胞定位
Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes. - Information by UniProt
-
数据库链接
- Entrez Gene: 51454 Human
- Entrez Gene: 70676 Mouse
- Entrez Gene: 314543 Rat
- Omim: 608165 Human
- SwissProt: Q9UBP9 Human
- SwissProt: Q8K2A1 Mouse
- SwissProt: Q5PQS4 Rat
- Unigene: 470887 Human
see all -
别名
- CED6 antibody
- Cell death protein 6 homolog antibody
- Engulfment adapter protein antibody
see all
图片
-
All lanes : Anti-GULP antibody (ab97669) at 1/1000 dilution
Lane 1 : HepG2 whole cell lysate
Lane 2 : MOLT4 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 35 kDa
10% SDS-PAGE. -
Anti-GULP antibody (ab97669) at 1/1000 dilution + NIH3T3 whole cell lysate at 30 µg
Predicted band size: 35 kDa
10% SDS-PAGE.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab97669 被引用在 1 文献中.
- Sullivan CS et al. The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism. Mol Biol Cell 25:1925-36 (2014). PubMed: 24743597