FITC荧光Anti-CD8 beta抗体[H35-17.2] (ab95773)
Key features and details
- FITC Rat monoclonal [H35-17.2] to CD8 beta
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Related conjugates and formulations
概述
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产品名称
FITC荧光Anti-CD8 beta抗体[H35-17.2]
参阅全部 CD8 beta 一抗 -
描述
FITC荧光大鼠单克隆抗体[H35-17.2] to CD8 beta -
宿主
Rat -
偶联物
FITC. Ex: 493nm, Em: 528nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CD8 beta. Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c
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阳性对照
- BALB/c Mouse splenocytes
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
H35-17.2 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95773于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use 0.125-0.25µg for 105-8 cells.
A final volume of 100 µL is recommended for staining the cell sample.
ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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说明 |
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Flow Cyt
Use 0.125-0.25µg for 105-8 cells. A final volume of 100 µL is recommended for staining the cell sample.
ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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靶标
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功能
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. -
组织特异性
Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells. Expression of isoform 6 is higher in peripheral CD8+ T-cells than in thymus CD8+ T-cells. -
序列相似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻译后修饰
Phosphorylated as a consequence of T-cell activation. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 12526 Mouse
- SwissProt: P10300 Mouse
- Unigene: 333148 Mouse
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别名
- CD8b antigen antibody
- CD_antigen=CD8b antibody
- CD8 antigen 37 kDa chain antibody
see all
图片
数据表及文件
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Datasheet download
文献 (3)
ab95773 被引用在 3 文献中.
- Thoma-Uszynski S et al. CD8alphaalpha T cells in lesions of Listeria monocytogenes-infected beta2m-deficient mice. Microb Pathog 23:101-6 (1997). PubMed: 9245621
- Tarleton RL et al. Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect Immun 62:1820-9 (1994). PubMed: 8168945
- Lefrancois L Phenotypic complexity of intraepithelial lymphocytes of the small intestine. J Immunol 147:1746-51 (1991). PubMed: 1716278