PE Anti-CD8 alpha抗体[EP72] (ab25436)
Key features and details
- PE Mouse monoclonal [EP72] to CD8 alpha
- Suitable for: IP, Flow Cyt, IHC-Fr, Purification
- Reacts with: Chicken
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2b
概述
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产品名称
PE Anti-CD8 alpha抗体[EP72]
参阅全部 CD8 alpha 一抗 -
描述
PE小鼠单克隆抗体[EP72] to CD8 alpha -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
ab25436 recognises alpha chain of chicken CD8. -
经测试应用
适用于: IP, Flow Cyt, IHC-Fr, Purificationmore details -
种属反应性
与反应: Chicken -
免疫原
Tissue, cells or virus corresponding to Chicken CD8 alpha. Chicken splenocytes
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Stabilising agent. -
Concentration information loading...
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纯度
Affinity purified -
克隆
单克隆 -
克隆编号
EP72 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25436于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IP |
Use at an assay dependent concentration.
|
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Flow Cyt |
Use at an assay dependent concentration.
ab91532 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
|
IHC-Fr |
Use at an assay dependent concentration.
Acetone fixed. |
|
Purification |
Use at an assay dependent concentration.
Purification of CD8+ T cells by positive cell sorting. |
说明 |
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IP
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab91532 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
IHC-Fr
Use at an assay dependent concentration. Acetone fixed. |
Purification
Use at an assay dependent concentration. Purification of CD8+ T cells by positive cell sorting. |
靶标
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功能
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. -
疾病相关
Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. -
序列相似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻译后修饰
All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
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别名
- alpha polypeptide (p32) antibody
- CD_antigen=CD8a antibody
- CD8 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab25436 尚未被引用在任何文献中。