Anti-CD42a/GP-IX抗体(ab88386)
Key features and details
- Mouse polyclonal to CD42a/GP-IX
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CD42a/GP-IX抗体
参阅全部 CD42a/GP-IX 一抗 -
描述
小鼠多克隆抗体to CD42a/GP-IX -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Full length native protein (purified) corresponding to Human CD42a/GP-IX.
Database link: AAH30229 -
阳性对照
- Human spleen tissue lysate and CD42a/GP-IX transfected 293T cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab88386于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 20 kDa).
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说明 |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 20 kDa). |
靶标
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功能
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. -
疾病相关
Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency. -
序列相似性
Contains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2815 Human
- Omim: 173515 Human
- SwissProt: P14770 Human
- Unigene: 1144 Human
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别名
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
see all
图片
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Anti-CD42a/GP-IX antibody (ab88386) at 1 µg/ml + human spleen tissue lysate at 50 µg
Predicted band size: 20 kDa
Observed band size: 18 kDa why is the actual band size different from the predicted? -
All lanes : Anti-CD42a/GP-IX antibody (ab88386) at 1 µg/ml
Lane 1 : CD42a/GP-IX transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 20 kDa
Observed band size: 18 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (0)
ab88386 尚未被引用在任何文献中。