FITC荧光Anti-CD2抗体[LT2] (ab27995)
Key features and details
- FITC Mouse monoclonal [LT2] to CD2
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Related conjugates and formulations
概述
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产品名称
FITC荧光Anti-CD2抗体[LT2]
参阅全部 CD2 一抗 -
描述
FITC荧光小鼠单克隆抗体[LT2] to CD2 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
特异性
ab27995 recognises CD2 expressed by T cells, NK cells and thymocytes. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD2. Normal human peripheral blood lymphocytes.
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常规说明
ab27995 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯度
Protein A purified -
Primary antibody说明
ab27995 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation. -
克隆
单克隆 -
克隆编号
LT2 -
骨髓瘤
x63-Ag8.653 -
同种型
IgG2b -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27995于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use 10µl for 106 cells.
Use 10µl for 106 cells, or 100µl of whole blood.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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说明 |
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Flow Cyt
Use 10µl for 106 cells. Use 10µl for 106 cells, or 100µl of whole blood.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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靶标
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功能
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. -
序列相似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 914 Human
- Omim: 186990 Human
- SwissProt: P06729 Human
- Unigene: 523500 Human
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别名
- CD 2 antibody
- CD2 antibody
- CD2 antigen (p50), sheep red blood cell receptor antibody
see all
图片
数据表及文件
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Datasheet download
文献 (2)
ab27995 被引用在 2 文献中.
- Lin CW et al. CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features. Blood 106:3567-74 (2005). PubMed: 16046525
- Beyers AD et al. Activation of T lymphocytes via monoclonal antibodies against rat cell surface antigens with particular reference to CD2 antigen. Immunol Rev 111:59-77 (1989). PubMed: 2576418