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RabMAb

Anti-CD1a抗体[EP3622] (ab108309)

概述

  • 产品名称
    Anti-CD1a抗体[EP3622]
    参阅全部 CD1a 一抗
  • 描述
    兔单克隆抗体[EP3622] to CD1a
  • 经测试应用
    适用于: WB, IHC-Pmore details
    不适用于: Flow Cyt,ICC or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues in human CD1a

  • 阳性对照
    • Human fetal thymus lysate, human T-78 cell lysate, human skin tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 解离常数(KD
    KD = 1.30 x 10 -11 M Learn more about KD
  • 存储溶液
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度
    Tissue culture supernatant
  • 克隆
    单克隆
  • 克隆编号
    EP3622
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab108309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC or IP.
  • 靶标

    • 功能
      Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
    • 组织特异性
      Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
    • 序列相似性
      Contains 1 Ig-like (immunoglobulin-like) domain.
    • 细胞定位
      Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 1a antibody
      • CD1 antibody
      • CD1a antibody
      • CD1A Antigen antibody
      • CD1A antigen, a polypeptide antibody
      • CD1a molecule antibody
      • CD1A_HUMAN antibody
      • cluster of differentiation 1 A antibody
      • cortical thymocyte antigen CD1A antibody
      • differentiation antigen CD1 alpha 3 antibody
      • epidermal dendritic cell marker CD1a antibody
      • FCB 6 antibody
      • FCB6 antibody
      • HTA 1 antibody
      • HTA1 antibody
      • hTa1 thymocyte antigen antibody
      • OTTHUMP00000018907 antibody
      • R 4 antibody
      • R4 antibody
      • T 6 antibody
      • T-cell surface antigen T6/Leu-6 antibody
      • T-cell surface glycoprotein CD1a antibody
      • T6 antibody
      see all

    Anti-CD1a antibody [EP3622] 图像

    • ab108309, at 1/250, staining CD1a in human skin tissue by immunohistochemistry
    • ab108309 showing positive staining in Normal tonsil tissue.

    • All lanes : Anti-CD1a antibody [EP3622] (ab108309) at 1/1000 dilution

      Lane 1 : Human fetal thymus lysate
      Lane 2 : T-78 cell lysate at 10 µg


      Performed under reducing conditions.

      Predicted band size : 37 kDa
    • ab108309 showing negative staining in Normal stomach tissue.

    • ab108309 showing negative staining in Normal uterus tissue.

    • ab108309 showing negative staining in Normal breast tissue.

    • ab108309 showing negative staining in Normal kidney tissue.

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-CD1a antibody [EP3622] (ab108309)参考文献

    This product has been referenced in:
    • Nguyen N  et al. Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma. Head Neck 38:1074-84 (2016). Human . Read more (PubMed: 26879675) »
    • Tam J  et al. Reconstitution of full-thickness skin by microcolumn grafting. J Tissue Eng Regen Med N/A:N/A (2016). IHC-P ; Human . Read more (PubMed: 27296503) »

    See all 3 Publications for this product

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    Thank you very much for your phone call.

    The best antibodies we can recommend are as follows. Please note that the recommendations are based on immunogen sequence only we currently do not hold any rabbit specific data.

    Anti CD3 : ab...

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    Thank you for contacting us. The immunogen of ab108309 is from amino acid XXXXXXXX of human CD1a protein. The immunogen of ab76531 is from amino acid XXXXXX of human CD1a. Click to check the compatible products: http://www.abcam.com/index.html?pageconf...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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