APC Anti-CD177抗体[MEM-166] (ab77230)
Key features and details
- APC Mouse monoclonal [MEM-166] to CD177
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
概述
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产品名称
APC Anti-CD177抗体[MEM-166]
参阅全部 CD177 一抗 -
描述
APC小鼠单克隆抗体[MEM-166] to CD177 -
宿主
Mouse -
偶联物
APC. Ex: 645nm, Em: 660nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human
预测可用于: Non human primates -
免疫原
Tissue, cells or virus corresponding to Human CD177. Human granulocytes
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阳性对照
- Human blood cells.
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常规说明
Purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.097% Sodium azide
Constituent: 0.2% BSA
0.2% (w/v) high-grade protease free BSA -
Concentration information loading...
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纯度
Size exclusion -
纯化说明
The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
克隆
单克隆 -
克隆编号
MEM-166 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab77230于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 10µl for 106 cells.
ab37391 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10µl for 106 cells or 100µl of whole blood. |
说明 |
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Flow Cyt
Use 10µl for 106 cells. ab37391 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10µl for 106 cells or 100µl of whole blood. |
靶标
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组织特异性
Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET). -
序列相似性
Contains 2 UPAR/Ly6 domains. -
翻译后修饰
N-glycosylated.
A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 57126 Human
- Omim: 162860 Human
- SwissProt: Q8N6Q3 Human
- Unigene: 232165 Human
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别名
- CD177 antibody
- CD177 antigen antibody
- CD177 molecule antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab77230 被引用在 3 文献中.
- Liu H et al. Proteinase 3 expression on the neutrophils of patients with paroxysmal nocturnal hemoglobinuria. Exp Ther Med 15:2525-2532 (2018). PubMed: 29467851
- Meyerson HJ et al. CD177 expression on neutrophils: in search of a clonal assay for myeloid neoplasia by flow cytometry. Am J Clin Pathol 140:658-69 (2013). PubMed: 24124144
- Zhou J et al. CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. J Exp Med 207:1951-66 (2010). Flow Cyt ; Human . PubMed: 20733031