Anti-BICD2抗体(ab73286)
Key features and details
- Rabbit polyclonal to BICD2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-BICD2抗体
参阅全部 BICD2 一抗 -
描述
兔多克隆抗体to BICD2 -
宿主
Rabbit -
特异性
this antibody does not cross react with BICD1. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to a 13 amino acid peptide from near the carboxy terminus of human BICD2.
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阳性对照
- A549 cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab73286于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa).
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说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa). |
靶标
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功能
May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. -
组织特异性
Ubiquitous. -
序列相似性
Belongs to the BicD family. -
结构域
The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2. -
翻译后修饰
Phosphorylated by NEK9 in vitro. -
细胞定位
Golgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology. - Information by UniProt
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数据库链接
- Entrez Gene: 23299 Human
- Omim: 609797 Human
- SwissProt: Q8TD16 Human
- Unigene: 436939 Human
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别名
- bA526D8.1 antibody
- Bic D 2 antibody
- Bic-D 2 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab73286 被引用在 1 文献中.
- Turgay Y et al. SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol 204:1099-109 (2014). PubMed: 24662567