Anti-Aspartate Aminotransferase抗体(ab85857)
Key features and details
- Goat polyclonal to Aspartate Aminotransferase
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Aspartate Aminotransferase抗体
参阅全部 Aspartate Aminotransferase 一抗 -
描述
山羊多克隆抗体to Aspartate Aminotransferase -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Rat, Pig, Chimpanzee, Cynomolgus monkey, Orangutan -
免疫原
Synthetic peptide:
RSYRYWDAEKR
by a Cysteine residue linker, corresponding to C terminal amino acids 157-167 of Human Aspartate Aminotransferase -
阳性对照
- Human kidney and heart tissue, Human Liver lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab85857于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 0.01 - 0.1 µg/ml. Predicted molecular weight: 46 kDa.
|
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IHC-P |
Use a concentration of 2.5 - 5 µg/ml.
|
说明 |
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WB
Use a concentration of 0.01 - 0.1 µg/ml. Predicted molecular weight: 46 kDa. |
IHC-P
Use a concentration of 2.5 - 5 µg/ml. |
靶标
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功能
Plays a key role in amino acid metabolism. -
序列相似性
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 450664 Chimpanzee
- Entrez Gene: 101865666 Cynomolgus monkey
- Entrez Gene: 2805 Human
- Entrez Gene: 100173864 Orangutan
- Entrez Gene: 396967 Pig
- Entrez Gene: 24401 Rat
- Omim: 138180 Human
- SwissProt: A5A6K8 Chimpanzee
see all -
别名
- AATC_HUMAN antibody
- Aspartate aminotransferase 1 antibody
- Aspartate aminotransferase antibody
see all
图片
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ab85857 at 5 µg/ml staining Aspartate Aminotransferase in formalin fixed and paraffin embedded Human Kidney tissue.
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ab85857 at 5 µg/ml staining Aspartate Aminotransferase in formalin fixed and paraffin embedded Human heart tissue.
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Anti-Aspartate Aminotransferase antibody (ab85857) at 0.01 µg/ml + Human Liver lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 46 kDa
Observed band size: 46 kDa
数据表及文件
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Datasheet download
文献 (3)
ab85857 被引用在 3 文献中.
- Guo Y et al. Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression. Cells 11:N/A (2022). PubMed: 36497150
- Untereiner AA et al. Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells. Biochem Pharmacol 149:174-185 (2018). WB . PubMed: 29061341
- Kästle M et al. Histone deacetylase 6 (HDAC6) plays a crucial role in p38MAPK-dependent induction of heme oxygenase-1 (HO-1) in response to proteasome inhibition. Free Radic Biol Med : (2012). PubMed: 23010497