HRP Anti-Apolipoprotein B抗体(ab27622)
Key features and details
- HRP Goat polyclonal to Apolipoprotein B
- Suitable for: ELISA, WB
- Reacts with: Human
- Conjugation: HRP
- Isotype: IgG
概述
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产品名称
HRP Anti-Apolipoprotein B抗体
参阅全部 Apolipoprotein B 一抗 -
描述
HRP山羊多克隆抗体to Apolipoprotein B -
宿主
Goat -
偶联物
HRP -
经测试应用
适用于: ELISA, WBmore details -
种属反应性
与反应: Human -
免疫原
Low Density Lipoproteins containing ApoB-100
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 6.50
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.134% PBS, 0.58% Sodium chloride, 1% BSA -
Concentration information loading...
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纯度
Affinity purified -
纯化说明
Purified by human apo B-100-Sepharose™ affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Recombinant Protein
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应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27622于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
|
|
WB |
Use at an assay dependent concentration.
|
说明 |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. -
疾病相关
Hypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. -
序列相似性
Contains 1 vitellogenin domain. -
翻译后修饰
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. -
细胞定位
Cytoplasm. Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 338 Human
- Omim: 107730 Human
- SwissProt: P04114 Human
- Unigene: 120759 Human
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别名
- Apo B 100 antibody
- Apo B antibody
- Apo B-100 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab27622 被引用在 3 文献中.
- Jones GM et al. Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method. J Lipid Res 61:455-463 (2020). PubMed: 31888979
- Gugliucci A et al. Small-dense low-density lipoproteins are the predominant apoB-100-containing lipoproteins in cord blood. Clin Biochem 47:475-7 (2014). WB ; Human . PubMed: 24362269
- Gugliucci A et al. Evidence for the presence of active paraoxonase 1 in small-dense low-density lipoprotein. Redox Rep 19:154-60 (2014). PubMed: 24524596