Anti-Apolipoprotein B抗体[7B8] (ab39560)
Key features and details
- Mouse monoclonal [7B8] to Apolipoprotein B
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
概述
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产品名称
Anti-Apolipoprotein B抗体[7B8]
参阅全部 Apolipoprotein B 一抗 -
描述
小鼠单克隆抗体[7B8] to Apolipoprotein B -
宿主
Mouse -
特异性
Ab39560 has specificity for Apolipoprotein B from serum/plasma. No crossreactivity is seen with Apolipoprotein A1. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Human LDL.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
7B8 -
骨髓瘤
x63-Ag8.653 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab39560于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/100 - 1/400.
|
说明 |
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IHC-P
1/100 - 1/400. |
靶标
-
功能
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. -
疾病相关
Hypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. -
序列相似性
Contains 1 vitellogenin domain. -
翻译后修饰
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. -
细胞定位
Cytoplasm. Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 338 Human
- Omim: 107730 Human
- SwissProt: P04114 Human
- Unigene: 120759 Human
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别名
- Apo B 100 antibody
- Apo B antibody
- Apo B-100 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling Apolipoprotein B with ab39560 at a dilution of 1/100. Signal is strong in the veins of the glomerulus.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human tonsil tissue labelling Apolipoprotein B with ab39560 at a dilution of 1/400. Plasma of the veins was stained strongly.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling Apolipoprotein B with ab39560 at a dilution of 1/400. Plasma veins were stained strongly.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab39560 被引用在 2 文献中.
- Arai C et al. Trehalose itself plays a critical role on lipid metabolism: Trehalose increases jejunum cytoplasmic lipid droplets which negatively correlated with mesenteric adipocyte size in both HFD-fed trehalase KO and WT mice. Nutr Metab (Lond) 17:22 (2020). PubMed: 32206077
- Seckler HDS et al. A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity. J Proteome Res 17:2156-2164 (2018). PubMed: 29649363