Anti-ARHGEF14抗体(ab96395)
Key features and details
- Rabbit polyclonal to ARHGEF14
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ARHGEF14抗体
参阅全部 ARHGEF14 一抗 -
描述
兔多克隆抗体to ARHGEF14 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment, corresponding to a region within amino acids 54-307 of Human ARHGEF14 (NP_001106203).
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阳性对照
- Molt-4 and Raji whole cell lysates; 293T, A431, H1299, HeLa and HepG2 whole cell lysate (ab7900)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96395于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 128 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 128 kDa. |
靶标
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功能
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42. -
序列相似性
Belongs to the MCF2 family.
Contains 1 CRAL-TRIO domain.
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
Contains 1 spectrin repeat. -
结构域
The CRAL-TRIO domain is involved in interaction with inositol phospholipids.
The DH domain is involved in interaction with CCPG1. -
细胞定位
Cytoplasm. Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 23263 Human
- Entrez Gene: 17207 Mouse
- Entrez Gene: 117020 Rat
- Omim: 609499 Human
- SwissProt: O15068 Human
- SwissProt: Q64096 Mouse
- SwissProt: Q63406 Rat
- Unigene: 170422 Human
see all -
别名
- ARHGEF 14 antibody
- DBL''s big sister antibody
- DBS antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab96395 尚未被引用在任何文献中。