Anti-AMBRA1抗体(ab69501)
Key features and details
- Rabbit polyclonal to AMBRA1
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-AMBRA1抗体
参阅全部 AMBRA1 一抗 -
描述
兔多克隆抗体to AMBRA1 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-P, WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human AMBRA1 (C terminal). AMBRA1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human AMBRA1 .
Database link: Q9C0C7 -
阳性对照
- WB: NIH/3T3 cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab69501于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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WB | (1) |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 143 kDa (predicted molecular weight: 143 kDa).
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说明 |
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ICC/IF
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 143 kDa (predicted molecular weight: 143 kDa). |
靶标
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功能
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. -
序列相似性
Contains 3 WD repeats. -
细胞定位
Cytoplasmic vesicle > autophagosome. - Information by UniProt
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数据库链接
- Entrez Gene: 55626 Human
- Entrez Gene: 228361 Mouse
- Omim: 611359 Human
- SwissProt: Q9C0C7 Human
- SwissProt: A2AH22 Mouse
- Unigene: 654644 Human
- Unigene: 436667 Mouse
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别名
- Activating molecule in beclin 1 regulated autophagy antibody
- Activating molecule in BECN1 regulated autophagy protein 1 antibody
- Activating molecule in BECN1-regulated autophagy protein 1 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab69501 被引用在 2 文献中.
- Siracusa R et al. Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis. Int J Mol Sci 22:N/A (2021). PubMed: 34064854
- Kim JH et al. Protective Effects of Evogliptin on Steatohepatitis in High-Fat-Fed Mice. Int J Mol Sci 21:N/A (2020). PubMed: 32937958