Anti-AFAP1L2抗体(ab106433)
Key features and details
- Rabbit polyclonal to AFAP1L2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-AFAP1L2抗体 -
描述
兔多克隆抗体to AFAP1L2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
A 15 amino acid synthetic peptide near the C terminus of Human AFAP1L2 (NP_001001936).
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阳性对照
- WB: Mouse liver tissue lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106433于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 91 kDa.
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说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 91 kDa. |
靶标
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功能
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. -
组织特异性
Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. -
序列相似性
Contains 2 PH domains. -
翻译后修饰
Tyrosine phosphorylated (by SRC). -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 226250 Mouse
- SwissProt: Q5DTU0 Mouse
- Unigene: 226284 Mouse
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别名
- Actin filament-associated protein 1-like 2 antibody
- AF1L2_HUMAN antibody
- AFAP1-like protein 2 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab106433 被引用在 3 文献中.
- Wang Q et al. XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells. Mol Carcinog 59:557-568 (2020). PubMed: 32159887
- Song K et al. Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels. Oncol Lett 20:68 (2020). PubMed: 32863901
- Shen J et al. XB130 enhances invasion and migration of human colorectal cancer cells by promoting epithelial-mesenchymal transition. Mol Med Rep 16:5592-5598 (2017). PubMed: 28849225