Anti-ABCC10抗体[M7I-3] (ab91451)
Key features and details
- Rat monoclonal [M7I-3] to ABCC10
- Suitable for: ICC
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ABCC10抗体[M7I-3]
参阅全部 ABCC10 一抗 -
描述
大鼠单克隆抗体[M7I-3] to ABCC10 -
宿主
Rat -
经测试应用
适用于: ICCmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment within Human ABCC10 aa 150-300 (internal sequence). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.3
Preservative: 0.1% Sodium azide
Constituent: 0.7% BSA
Serum free tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
M7I-3 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab91451于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC |
1/20 - 1/50.
Acetone fixed cytospin preparations. |
说明 |
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ICC
1/20 - 1/50. Acetone fixed cytospin preparations. |
靶标
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功能
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. -
组织特异性
Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed. -
序列相似性
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 89845 Human
- Omim: 612509 Human
- SwissProt: Q5T3U5 Human
- Unigene: 55879 Human
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别名
- ABCC10 antibody
- ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
- ATP binding cassette, subfamily C, member 10 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab91451 被引用在 8 文献中.
- Shi B et al. Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells. Oncol Lett 20:148 (2020). PubMed: 32934716
- Wang X et al. SDF-1a/MicroRNA-134 Axis Regulates Nonfunctioning Pituitary Neuroendocrine Tumor Growth via Targeting VEGFA. Front Endocrinol (Lausanne) 11:566761 (2020). PubMed: 33362712
- Wei W et al. The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1. Oncol Res 28:423-438 (2020). PubMed: 32331534
- Orellana-Serradell O et al. The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines. Asian J Androl N/A:N/A (2019). PubMed: 30880686
- Wang H et al. Effects of histone deacetylase inhibitors on ATP-binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells. Oncol Lett 18:63-71 (2019). PubMed: 31289473
- Zhang L et al. miR-361 enhances sensitivity to 5-fluorouracil by targeting the FOXM1-ABCC5/10 signaling pathway in colorectal cancer. Oncol Lett 18:4064-4073 (2019). PubMed: 31579069
- Xu R & Han Y Long non-coding RNA FOXF1 adjacent non-coding developmental regulatory RNA inhibits growth and chemotherapy resistance in non-small cell lung cancer. Arch Med Sci 15:1539-1546 (2019). PubMed: 31749883
- De Souza R et al. Chemotherapy dosing schedule influences drug resistance development in ovarian cancer. Mol Cancer Ther 10:1289-99 (2011). WB ; Mouse . PubMed: 21551263