8-Br-cGMP (8-Bromo-cGMP),PKG活化剂(ab141449)
Key features and details
- Cell permeable cGMP analog. PKG activator.
- CAS Number: 51116-01-9
- Purity: > 95%
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
8-Br-cGMP (8-Bromo-cGMP),PKG活化剂 -
描述
Cell permeable cGMP analog. PKG活化剂. -
纯度
> 95% -
常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 1838 8-Br-cGMP. 1838-25 is the same size as the 25 mg size of ab141449.
-
CAS编号
51116-01-9 -
化学结构
性能
-
化学名称
2-Amino-8-bromo-9-(7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-3H-purin-6-one sodium salt -
分子量
446.08 -
分子式
C10H10BrN5NaO7P -
PubChem识别号
44134592 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1C2C(C(C(O2)N3C4=C(C(=O)N=C(N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+] -
来源
Synthetic
-
研究领域
相关产品
-
Related Products
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab141449 被引用在 2 文献中.
- Cao S et al. Effects of cGMP/Akt/GSK-3β signaling pathway on atrial natriuretic peptide secretion in rabbits with rapid atrial pacing. Front Physiol 13:861981 (2022). PubMed: 36060704
- Gu M et al. Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart. Front Cell Dev Biol 9:774185 (2021). PubMed: 35155444