Anti-5HT4 Receptor抗体(ab219116)
Key features and details
- Rabbit polyclonal to 5HT4 Receptor
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-5HT4 Receptor抗体
参阅全部 5HT4 Receptor 一抗 -
描述
兔多克隆抗体to 5HT4 Receptor -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Gorilla -
免疫原
Synthetic peptide corresponding to Human 5HT4 Receptor. (A 15 amino acid peptide from the 3rd cytoplasmic domain).
Database link: Q13639 -
阳性对照
- Human brain, medulla tissue; Human brain, glioblastoma tissue; Human skin, Melanoma tissue; Human prostate tissue; Human kidney tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.099% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab219116于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 15 - 20 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 15 - 20 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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相关性
The 5HT4 Receptor is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulates adenylate cyclase. 5HT4a receptors may play a role in opioid-induced respiratory depression. -
细胞定位
Cell membrane; Multi-pass membrane protein. Endosome. Note: Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. -
数据库链接
- Entrez Gene: 317708 Cow
- Entrez Gene: 489198 Dog
- Entrez Gene: 101142127 Gorilla
- Entrez Gene: 100135548 Guinea pig
- Entrez Gene: 100034053 Horse
- Entrez Gene: 3360 Human
- Entrez Gene: 15562 Mouse
- Entrez Gene: 397431 Pig
see all -
别名
- 5 HT 4 antibody
- 5 HT4 antibody
- 5 HT4R antibody
see all
图片
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain (medulla) tissue labeling 5HT4 with ab219116 at 20 µg/ml.
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain (glioblastoma) tissue labeling 5HT4 with ab219116 at 20 µg/ml.
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human skin (melonoma) tissue labeling 5HT4 with ab219116 at 20 µg/ml.
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human prostate tissue labeling 5HT4 with ab219116 at 20 µg/ml.
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human kidney tissue labeling 5HT4 with ab219116 at 20 µg/ml.
数据表及文件
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Datasheet download
文献 (0)
ab219116 尚未被引用在任何文献中。