Anti-5HT2A Receptor抗体(ab85496)

概述

  • 产品名称Anti-5HT2A Receptor抗体
    参阅全部 5HT2A Receptor 一抗
  • 描述
    兔多克隆抗体to 5HT2A Receptor
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Pig, Chimpanzee
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN) of human 5HT2A Receptor (NP_000612).

  • 阳性对照
    • 721_B cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab85496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 结构域The PDZ domain-binding motif is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.
  • 细胞定位Cell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5 HT 2 antibody
    • 5 HT 2A antibody
    • 5 HT2 receptor antibody
    • 5 HT2A antibody
    • 5 hydroxytryptamine receptor 2A antibody
    • 5-HT-2 antibody
    • 5-HT-2A antibody
    • 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled antibody
    • 5-hydroxytryptamine 2A receptor antibody
    • 5-hydroxytryptamine receptor 2A antibody
    • 5HT2A_HUMAN antibody
    • HTR 2 antibody
    • HTR 2A antibody
    • HTR2 antibody
    • HTR2, formerly antibody
    • HTR2A antibody
    • serotonin 5-HT-2 receptor, formerly antibody
    • serotonin 5-HT-2A receptor antibody
    • Serotonin receptor 2A antibody
    see all

Anti-5HT2A Receptor antibody 图像

  • Anti-5HT2A Receptor antibody (ab85496) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 53 kDa
    Observed band size : 53 kDa
    Additional bands at : 65 kDa. We are unsure as to the identity of these extra bands.

Anti-5HT2A Receptor antibody (ab85496)参考文献

ab85496 has not yet been referenced specifically in any publications.

Product Wall

I can confirm that this antibody already contains a cryoprotectant, sucrose. It will therefore not require any addition of glycerol or other preservative before refreezing.

We do recommend to avoid freeze thaw cycles. If the customer is not ...

Read More

Thanks for your email.

Indeed, with corresponding antibody I meant ab16028.

The anti-5HT2A Receptor ab85496 may or may not detect the peptide ab16195, although to our knowledge this has not been tested yet.

The ab16195 ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"