Anti-5-Hydroxymethyluridine抗体(ab19735)
Key features and details
- Goat polyclonal to 5-Hydroxymethyluridine
- Suitable for: IP, ELISA
- Reacts with: Species independent
- Isotype: IgG
概述
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产品名称
Anti-5-Hydroxymethyluridine抗体 -
描述
山羊多克隆抗体to 5-Hydroxymethyluridine -
宿主
Goat -
经测试应用
适用于: IP, ELISAmore details -
种属反应性
与反应: Species independent -
免疫原
5-Hydroxymethyluridine coupled to a carrier protein.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.1% Sodium azide -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab19735于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IP |
Use at an assay dependent concentration. PubMed: 22514282
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ELISA |
1/25000.
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说明 |
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IP
Use at an assay dependent concentration. PubMed: 22514282 |
ELISA
1/25000. |
靶标
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相关性
5 Hydroxymethyluridine is formed from thymidine during the oxidation of DNA by ionizing radiation or reactive oxygen species (ROS) that are formed from inflammatory response. This causes genetic mutations, altered gene expression and chromosomal instability that has generally been implicated with aging, cancers and autoimmune disease. -
别名
- 5 HmdU antibody
- 5 Hydroxymethyl 2’ deoxyuridine antibody
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab19735 被引用在 3 文献中.
- Herrmann A et al. Integrin a6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cells. Oncogene 39:2156-2169 (2020). PubMed: 31819166
- Yakovlev IA et al. Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome. Sci Rep 9:19314 (2019). PubMed: 31848418
- Cliffe LJ et al. JBP1 and 2 are Fe2+/2-OG dependent dioxygenases regulating the hydroxylation of thymidine residues in trypanosome DNA. J Biol Chem : (2012). IP . PubMed: 22514282