概述

  • 产品名称17β-Estradiol
  • 描述
    Selective agonist of ER receptor
  • 生物学描述Selective agonist of ER receptor. Binds to ERα and ERβ receptors (Ki values are 0.13 and 0.12 nM, respectively). Agonist at the GPR30 receptor, activates PI3K.
  • 纯度> 99%

性能

    17β-Estradiol (ab120657)参考文献

    This product has been referenced in:
    • Hernández-Fonseca K  et al. Neuroprotective Role of Estradiol against Neuronal Death Induced by Glucose Deprivation in Cultured Rat Hippocampal Neurons. Neuroendocrinology : (2011). Read more (PubMed: 22213775) »
    • Maggiolini M & Picard D The unfolding stories of GPR30, a new membrane-bound estrogen receptor. J Endocrinol 204:105-14 (2010). Read more (PubMed: 19767412) »
    • Thomas P  et al. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146:624-32 (2005). Read more (PubMed: 15539556) »
    • Kuiper GG  et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138:863-70 (1997). Read more (PubMed: 9048584) »

    See all 2 Publications for this product

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    We have tested the solubility of this product in our lab and found that it is soluble in DMSO and in ethanol to the limits stated on the datasheet; this product is not soluble in water. Unfortunately, we do not offer a...

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