Anti-17 beta Estradiol 6抗体[7G4] (ab23449)

概述

  • 产品名称Anti-17 beta Estradiol 6抗体[7G4]
  • 描述
    小鼠单克隆抗体[7G4] to 17 beta Estradiol 6
  • 特异性ab23449 reacts with estradiol-17beta. No crossreactivity is seen with estrone, esrriol, estrone sulphate, 16-ketoestradiol, 2-hydroxyestradiol, progesterone, androstenedione, testosterone, or cortisol when measuring on tritium-labeled steroids in radioimmunoassay.
  • 经测试应用适用于: ELISAmore details
  • 免疫原

    Estradiol-17b-6-CMO coupled to BSA

  • 表位Epitope specific for the hormone, no reactivity to the CMO linker
  • 常规说明


    HYB 057-02 reacts specifically with estradiol-17beta with a measured Ka of 3x10E9 in a radioimmunoassay. HYB 057-02 can be cleaved with papain and reduced to generate Fab fragments with a Ka of 13.4x10E9

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein A purified
  • Primary antibody说明HYB 057-02 reacts specifically with estradiol-17beta with a measured Ka of 3x10E9 in a radioimmunoassay. HYB 057-02 can be cleaved with papain and reduced to generate Fab fragments with a Ka of 13.4x10E9
  • 克隆单克隆
  • 克隆编号7G4
  • 骨髓瘤P3x63-Ag8.653
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1500.

靶标

  • 相关性Estradiol is the most potent estrogen of a group of endogenous estrogen steroids which includes estrone and estriol. In women estradiol is responsible for growth of the breast and reproductive epithelia, maturation of long bones and development of the secondary sexual characteristics. Estradiol is produced mainly by the ovaries with secondary production by the adrenal glands and conversion of steroid precursors into estrogens in fat tissue.
  • 细胞定位Type I Membrane
  • 别名
    • Estradiol 17 beta antibody

Anti-17 beta Estradiol 6 antibody [7G4] (ab23449)参考文献

This product has been referenced in:
  • Pajunen M  et al. Cloning, sequencing, expression and characterization of three anti-estradiol-17beta Fab fragments. Biochim Biophys Acta 1351:192-202 (1997). Read more (PubMed: 9116033) »
  • Lamminmäki U  et al. Structural analysis of an anti-estradiol antibody. Mol Immunol 34:1215-26 (1997). Read more (PubMed: 9566768) »

See all 2 Publications for this product

Product Wall

Thank you for your patience in this matter. The originator of ab23449 (17 beta Estradiol 6 antibody [HYB 057-02]) has informed us that the product has been processed to prevent reaction with BSA, so there is only reaction with beta estradiol. I w...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"