Anti-15-LOX-2抗体(ab23691)
Key features and details
- Rabbit polyclonal to 15-LOX-2
- Suitable for: WB
- Reacts with: Human, Pig
- Isotype: IgG
概述
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产品名称
Anti-15-LOX-2抗体
参阅全部 15-LOX-2 一抗 -
描述
兔多克隆抗体to 15-LOX-2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human, Pig
不与反应: Rabbit -
免疫原
Synthetic peptide corresponding to Human 15-LOX-2 aa 163-181.
Sequence:CLDEKTVEDLELNIKYSTA
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阳性对照
- Human prostate homogenate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 50% Glycerol, 0.1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
This antibody was affinity purified. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab23691于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 3 µg/ml. Predicted molecular weight: 76 kDa.
Or 1/200. |
说明 |
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WB
Use a concentration of 3 µg/ml. Predicted molecular weight: 76 kDa. Or 1/200. |
靶标
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功能
Converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while linoleic acid is less well metabolized. -
组织特异性
Expressed in hair, prostate, lung and cornea. -
通路
Lipid metabolism; leukotriene D4 biosynthesis. -
序列相似性
Belongs to the lipoxygenase family.
Contains 1 lipoxygenase domain.
Contains 1 PLAT domain. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 247 Human
- Omim: 603697 Human
- SwissProt: O15296 Human
- Unigene: 111256 Human
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别名
- 15 Lipoxygenase 2 antibody
- 15 LO 2 antibody
- 15 LOX 2 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (14)
ab23691 被引用在 14 文献中.
- Dar HH et al. P. aeruginosa augments irradiation injury via 15-lipoxygenase-catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis. JCI Insight 7:N/A (2022). PubMed: 35041620
- Miek L et al. Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology 166:47-67 (2022). PubMed: 35143048
- Zhang K et al. Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization. J Inflamm Res 15:3285-3304 (2022). PubMed: 35676971
- Van Anh TT et al. From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution. Acta Pharm Sin B 11:1629-1647 (2021). PubMed: 34221873
- Zhao D et al. Enteral nutrition ameliorates the symptoms of Crohn's disease in mice via activating special pro-resolving mediators through innate lymphoid cells. Innate Immun 27:533-542 (2021). PubMed: 34791916