概述

  • 产品名称1400W
  • 描述
    Selective iNOS inhibitor
  • 生物学描述Selective iNOS inhibitor, 5000-fold selective over eNOS (Kd values are ≤7 nM, 2 μM and 50 μM at human iNOS, nNOS and eNOS, respectively).
  • 纯度> 99%

性能

    1400W (ab120165)参考文献

    This product has been referenced in:
    • Hamilton LC & Warner TD Interactions between inducible isoforms of nitric oxide synthase and cyclo-oxygenase in vivo: investigations using the selective inhibitors, 1400W and celecoxib. Br J Pharmacol 125:335-40 (1998). Read more (PubMed: 9786506) »
    • Garvey EP  et al. 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem 272:4959-63 (1997). Read more (PubMed: 9030556) »
    • Thomsen LL  et al. Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. Cancer Res 57:3300-4 (1997). Read more (PubMed: 9242464) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120165.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"