Anti-14-3-3 zeta抗体, prediluted (ab32623)

概述

  • 产品名称Anti-14-3-3 zeta抗体, prediluted
    参阅全部 14-3-3 zeta 一抗
  • 描述
    兔多克隆抗体to 14-3-3 zeta, prediluted
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    AGDDKKGIVDQSQQAY

    , corresponding to amino acids 134-149 of Human 14-3-3 zeta

  • 阳性对照
    • NIH3T3 cells. Breast carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab32623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
WB 1/1.

靶标

  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻译后修饰The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53. This phosphorylation appears to be activated by sphingosine. Phosphorylation on Thr-232; inhibits binding of RAF1.
  • 细胞定位Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14 3 3 delta antibody
    • 14 3 3 protein zeta/delta antibody
    • 14 3 3 protein/cytosolic phospholipase A2 antibody
    • 14 3 3 zeta antibody
    • 14-3-3 protein zeta/delta antibody
    • 1433Z_HUMAN antibody
    • Epididymis luminal protein 4 antibody
    • Epididymis secretory protein Li 3 antibody
    • HEL S 3 antibody
    • HEL4 antibody
    • KCIP-1 antibody
    • KCIP1 antibody
    • MGC111427 antibody
    • MGC126532 antibody
    • MGC138156 antibody
    • Phospholipase A2 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody
    • Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody
    • YWHAD antibody
    • YWHAZ antibody
    see all

Anti-14-3-3 zeta antibody, prediluted 图像

  • IHC staining of formalin-fixed, paraffin-embedded human breast carcinoma with prediluted ab32623.
  • Anti-14-3-3 zeta antibody (ab32622) at 1/25 dilution + lysate prepared from 293 cells

    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

Anti-14-3-3 zeta antibody, prediluted (ab32623)参考文献

ab32623 has not yet been referenced specifically in any publications.

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