Anti-14-3-3 Tau (phospho S232)抗体(ab63369)

概述

  • 产品名称Anti-14-3-3 Tau (phospho S232)抗体
    参阅全部 14-3-3 Tau 一抗
  • 描述
    兔多克隆抗体to 14-3-3 Tau (phospho S232)
  • 特异性ab63369 detects 14-3-3 Tau only when phosphorylated at serine 232.
  • 经测试应用适用于: ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to Human 14-3-3 Tau (phospho S232). (S-D-SP-A-G).
    Database link: P27348

  • 阳性对照
    • ICC/IF: HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab63369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
  • 组织特异性Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻译后修饰Ser-232 is probably phosphorylated by CK1.
  • 细胞定位Cytoplasm. In neurons, axonally transported to the nerve terminals.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14 3 3 protein T cell antibody
    • 14 3 3 protein tau antibody
    • 14 3 3 protein theta antibody
    • 14 3 3 tau antibody
    • 14 3 3 theta antibody
    • 14-3-3 protein T-cell antibody
    • 14-3-3 protein tau antibody
    • 14-3-3 protein theta antibody
    • 1433T_HUMAN antibody
    • 1C5 antibody
    • HS1 antibody
    • KCIP1 antibody
    • Protein HS1 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Protein tau antibody
    • tyr3/trp5 monooxygenase activation protein, theta antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide antibody
    • Ywhaq antibody
    see all

Anti-14-3-3 Tau (phospho S232) antibody 图像

  • ab63369 at 1/500 dilution staining 14-3-3 Tau in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.

Anti-14-3-3 Tau (phospho S232) antibody (ab63369)参考文献

ab63369 has not yet been referenced specifically in any publications.

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