Anti-14-3-3抗体[3F7] (ab14108)

概述

  • 产品名称Anti-14-3-3抗体[3F7]
    参阅全部 14-3-3 一抗
  • 描述
    小鼠单克隆抗体[3F7] to 14-3-3
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human 14-3-3 gamma).

  • 阳性对照
    • HeLa whole cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab14108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 30 kDa.
IP Use at an assay dependent dilution.

靶标

  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻译后修饰The alpha, brain-specific form differs from the beta form in being phosphorylated (By similarity). Phosphorylated on Ser-60 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion.
    Isoform Short contains a N-acetylmethionine at position 1.
  • 细胞定位Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14 3 3 antibody
    • 14 3 3 protein beta antibody
    • 14 3 3 protein beta/alpha antibody
    • 14 3 3 protein zeta antibody
    • 14 3 3 zeta antibody
    • 14-3-3 protein beta/alpha antibody
    • 14-3-3 protein/cytosolic phospholipase A2 antibody
    • 1433B_HUMAN antibody
    • GW128 antibody
    • HS1 antibody
    • KCIP 1 antibody
    • KCIP-1 antibody
    • MGC111427 antibody
    • MGC126532 antibody
    • MGC138156 antibody
    • N-terminally processed antibody
    • Protein 1054 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide antibody
    • Tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide antibody
    • YWHAB antibody
    • YWHAD antibody
    • YWHAZ antibody
    see all

Anti-14-3-3 antibody [3F7] (ab14108)参考文献

ab14108 has not yet been referenced specifically in any publications.

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