Anti-14-3-3 alpha + beta抗体(ab113769)

概述

  • 产品名称Anti-14-3-3 alpha + beta抗体
    参阅全部 14-3-3 alpha + beta 一抗
  • 描述
    兔多克隆抗体to 14-3-3 alpha + beta
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 34-211 of Human 14-3-3 alpha + beta

  • 阳性对照
    • Raji whole cell lysate, Human Cerebellum and Human Skin tissues, HeLa cells

性能

应用

Our Abpromise guarantee covers the use of ab113769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/20000. Predicted molecular weight: 28 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻译后修饰The alpha, brain-specific form differs from the beta form in being phosphorylated.
    Isoform Short contains a N-acetylmethionine at position 1.
  • 细胞定位Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14 3 3 alpha antibody
    • 14 3 3 protein beta/alpha antibody
    • 14-3-3 protein beta/alpha antibody
    • 1433B_HUMAN antibody
    • Brain protein 14 3 3 beta isoform antibody
    • GW128 antibody
    • HS 1 antibody
    • KCIP-1 antibody
    • KCIP1 antibody
    • N-terminally processed antibody
    • Protein 1054 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • YWHAA antibody
    • YWHAB antibody
    see all

Anti-14-3-3 alpha + beta antibody 图像

  • Anti-14-3-3 alpha + beta antibody (ab113769) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 28 kDa
  • Staining of Human 14-3-3 alpha + beta in a Formalin/PFA-fixed paraffin-embedded section of Human Cerebellum using ab113769 at a concentration of 5 µg/ml.
  • Staining of Human 14-3-3 alpha + beta in a Formalin/PFA-fixed paraffin-embedded section of Human Skin using ab113769 at a concentration of 5 µg/ml.
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ab113769 at a dilution of 1/200. Lower picture merged with DNA probe.

Anti-14-3-3 alpha + beta antibody (ab113769)参考文献

ab113769 has not yet been referenced specifically in any publications.

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